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July 15, 2009

Why Women and Men Have Differences in Disease Progression

"A study, published July 13 online in Nature Medicine, has discovered why HIV-positive women have faster disease progression than HIV-positive men with the same viral loads. The answer may be greater levels of immune inflammation.

"Though taken as a whole, women do not appear to have faster disease progression than men, it is well known that their viral loads and CD4 counts may differ from what is common in men. Women’s immune systems bring virus levels under better control than men’s systems soon after becoming infected with HIV. However, researchers have also discovered that when women and men with the same viral loads are compared, women generally progress faster. Until now, no one has proved why this is the case.
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Read more in POZ, July 14, 2009.

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