Inflammation and mortality in HIV-infected adults: analysis of the FRAM study cohort.

JAIDS: "CONCLUSIONS: Fibrinogen and CRP [C-reactive protein] are strong and independent predictors of mortality in HIV-infected adults. Our findings suggest that even in those with relatively preserved CD4 counts >500 cells per microliter, inflammation remains an important risk factor for mortality. Further investigation should determine whether interventions to reduce inflammation might decrease mortality risk in HIV-infected individuals."